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Simon sources information by combining Scholars in Medicine's extensive educational content and clinician-developed materials with trusted medical sources across the web. While Simon prioritizes high-quality resources, AI-generated content may be incomplete or inaccurate. Simon is designed to supplement, not replace, clinical judgment and professional medical expertise. Always verify information and consult healthcare professionals for clinical decision-making.

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Simon sources information by combining Scholars in Medicine's extensive educational content and clinician-developed materials with trusted medical sources across the web. While Simon prioritizes high-quality resources, AI-generated content may be incomplete or inaccurate. Simon is designed to supplement, not replace, clinical judgment and professional medical expertise. Always verify information and consult healthcare professionals for clinical decision-making.

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Case Studies

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May 27, 2026

68M, Nasal Ala Lesion

A 68-year-old man presents with a slowly enlarging pearly papule on the right nasal ala that intermittently crusts and bleeds. He has a history of significant sun exposure and prior actinic keratoses. On exam, there’s a 1.1-cm translucent papule with rolled borders and telangiectasias. Palpation reveals subtle firmness at the periphery but no regional adenopathy. Shave biopsy: basaloid proliferation with stromal retraction and focal infiltrative pattern.

Labs: normal.

Past medical history: CAD, controlled with beta-blocker.

Diagnose
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May 19, 2026

24F, Pruritic Shoulder Mass After Piercing

A 24-year-old woman with Fitzpatrick IV skin presents with a firm, dome-shaped, lobulated scar over the right posterior shoulder that enlarged over 14 months after a deltoid piercing. It is shiny, hyperpigmented, pruritic, and occasionally tender; borders extend beyond the original piercing tract. No drainage. She tried OTC silicone gel intermittently.

Exam: 3.5 × 2.0 cm rubbery plaque with telangiectasias and “claw-like” extension; no fluctuance. Vitals normal. Labs (selected): CBC, TSH normal; A1c 5.3%. She is cosmetically distressed; works as a barista. No keloids elsewhere; no isotretinoin; uses estrogen OCP.

Diagnose
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May 13, 2026

62M, Flaccid Blisters on Trunk with Rapid Crusting

A 62-year-old man with type 2 diabetes (A1c 8.4%) and chronic venous stasis presents with 3 days of rapidly enlarging flaccid bullae on the lower abdomen and proximal thighs that rupture, leaving thin varnish-like crusts. Mild malaise, no fever. Works as a wrestling coach; recent friction injuries.

Meds: metformin, lisinopril. NKDA.

Exam: several 2–3 cm superficial bullae; after rupture, shallow erosions with thin crust; Nikolsky negative; no mucosal lesions. No cellulitis or abscess.

Vitals stable. He can’t easily keep dressings on due to sweat; lesions >10% BSA.

Diagnose
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March 31, 2026
Diagnose

29F, Recurrent Painful Axillary Nodules

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March 31, 2026
Diagnose

6F, Beard-area Plaques + Intermittent Biphasic Stridor

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March 25, 2026
Diagnose

68M, Pruritic Truncal Papules After Heat Exposure

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March 24, 2026
Diagnose

46F, Annular Papules on Hands and Forearms

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March 15, 2026
Diagnose

72M, rapidly enlarging ulcerated scalp nodule

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March 10, 2026
Diagnose

42F, Pruritic Erythematous Plaques on Hands

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March 5, 2026
Diagnose

24F, Tender Axillary Node + Papule on Forearm

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March 3, 2026
Diagnose

16F, Episodic Leg Mottling + Lightheadedness

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January 28, 2026
Diagnose

6F, Beard-area Plaques + Intermittent Biphasic Stridor

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January 18, 2026
Diagnose

52F, Inflammatory papules, erythema and flushing

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December 10, 2025
Diagnose

32F, Rapid patchy hair loss

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August 12, 2024
Diagnose

Photodermatoses - Case 1

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August 12, 2024
Diagnose

Varicella - Case 1

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July 31, 2024
Diagnose

Exanthems - Case 1

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July 31, 2024
Diagnose

Vascular Stains - Case 1